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TurboGears will help you to create a database-driven, ready-to-extend application in minutes. All with designer friendly templates, easy AJAX on the browser side and on the server side, with an incredibly powerful and flexible Object Relational Mapper (ORM), and with code that is as natural as writing a function.
Equally importantly, when you need more, TurboGears has the tools to help you out. Multi-database support, super-scalable encrypted cookie sessions, and many other great helpers are there out of the box. And we don't stop there, TurboGears is built on top of standard WSGI components, so it's easy to customize the framework to meet your specific needs.
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It's a mix of some underlying python technologies. If you're not going for Django and want to use some techs like Elixir, Pylons, Formencode, Genshi, go ahead for Turbohgears - it will have those connected for You.
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It's a really cool web framework actually. A nice alternative to Django (which I think dominates in Python web frameworks). Although the documentation is really crappy.